No matter what I try the latest version in the system will be 4.0.ĭirectX 9. If your GPU supports 3.0 then the version of Shader Model will be 3.0 ![]() Given 2 graphs, one contains the set of all vertices that can be reached from one starting vertex, the other contains the set of all vertices that can be reached from another starting vertex, how can I calculate the intersection of the two graphs? These results are consistent with the notion that MHC class II-restricted, antigen-specific helper T cells can be involved in the pathogenesis of autoimmune disease.Q: Thus, although GP and LDA share the MHC class II-restricted element, LDA-stimulated macrophages can express IL-1 mRNA whereas GP-stimulated macrophages can express IL-2 and IL-4 mRNA. In macrophages, LDA induced IL-1 and IL-6 mRNA whereas GP induced IL-1 mRNA. LDA induced the production of IL-2 and IL-4 mRNAs in B cells whereas GP induced production of both IL-2 and IL-4 mRNA. Cytokine mRNA expression was measured in LDA- or GP-stimulated, primary, B cell or macrophage cultures using a RT-PCR assay. In contrast, GP induced a T cell-mediated helper response. LDA induced a T cell-mediated suppression of autoimmunity in the EAE model. ![]() To determine whether a class II-restricted pathogenic T cell response is due to failure of class II-restricted helper T cells to activate class II-restricted regulatory T cells, the differential induction of cytokine mRNA expression by two MHC class II-restricted epitopes, MHC class II-restricted helper peptide (GP) and MHC class II-restricted regulatory peptide (LDA), was examined. ![]() 0 with exception of deferred lighting.Elicitation of specific murine cytokine mRNA expression by two distinct major histocompatibility complex class II epitopes presented by B cells and macrophages in a murine model of autoimmunity.Īutoimmune disease often is associated with the failure of both helper and suppressor T cells to recognize autologous antigen in the context of MHC class II molecules. Maxwell FX 9600 GT is capable of running Shader Model 3. JanuMicrosoft DirectX9.0c Shader Model 3.0
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